Sydney According to a new study, eating right has a much stronger effect on how our cells work than taking medication.
The results of this study will be published in the Cell Metabolism Journal.
A clinical study from the University of Sydney's Charles Perkins Center suggests that the composition of our diet may be more important than drugs in keeping diseases like diabetes, stroke, and heart disease at bay.
A study in mice showed that diet had a smaller impact on aging and metabolic health than the three drugs commonly used to treat diabetes and destroy aging.
This study builds on the pioneering work of platooning in mice and humans and demonstrates the protective part of the diet and specific combinations of protein, fat, and carbohydrates against aging, roundness, heart disease, prone dysfunction, and problems with a metabolic disease similar to the type. 2 diabetes.
Diet is an important medicine. However, drugs are currently being administered without considering whether and how they might interact with our diets if they act in the same way and through the same nutritional signaling pathways as diet, Professor Simpson said.
Researchers are beginning to find out whether drugs or diet are more important, to rethink views of nutrition and other metabolic pathways, and whether drugs and diet interact in ways that make them more or less effective.
We found that the therapeutic composition had a much more important effect than not changing the drug, which greatly reduced the response to diet, said Professor Simpson.
Given that humans engage in essentially the same nutritional signaling pathways as mice, this study suggests that humans would benefit better from changing their diet to improve metabolic health than using the drugs we examined, Simpson added.
The research train designed a complex study in mice that included 40 different treatments, each with a different protein, fat, and carbohydrate balance situation, calories, and drug content.
This study aimed to investigate the effect of three growth-inhibiting drugs on the liver, which is an important organ in regulating metabolism.
The main strength of this study is the use of the geometric nutritional framework developed by Professors Stephen Simpson and David Raubenheimer. This framework allows the train to assess how the combining and combination of different nutrients indicates health and disease, rather than being tied to one nutrient separately, which is a limitation in other nutrition studies.
The results contribute to confusing our understanding of the mechanisms linking our diet to our progress.
Calories imported into experimental plants and the balance of macronutrients in the diet have a profound effect on the liver.
Imported protein and total calories have a very important impact not only on metabolic pathways but also on the alphabetical processes that govern the way our cells serve.
As an illustration, the amount of protein ingested indicates an effort in the mitochondria, which are the part of the cell that produces energy.
This creates a downstream effect as useful amounts of protein and energy suffer from how cells directly reformulate their genes into the various proteins needed to help cells function properly and make new cells.
Both of these alphabetical processes are associated with aging.
In comparison, drugs work significantly to reduce the metabolic response of cells to nutrients rather than forming them naturally.
However, the researchers also found some additional specific relationships between drug biochemical products and food composition.
Anti-growth drugs have a greater effect on cellular changes caused by beneficial fats and carbohydrates, while other cancers and diabetes drugs block beneficial protein products in the mitochondria that produce energy.
Lead author Professor David Le Cooter of the Charles Perkins Center and School of Medicine and Health said that while the study was very complex, it had demonstrated the importance of studying many different diets at the same time rather than just following many different diets to compare.
This is the only way to get an idea of the trade between nutrition, health, and physiology says, Professor Le Cooter.
We all know that what we eat affects our health, but this research shows how food can drastically affect many processes in our cells. This gives us an understanding of how diet affects health and aging, he added.
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